Pretty much what most everyone said but entry and exit to and from any set up undetected is paramount, IMO. Funnels or buck travel corridors from bedding area to other bedding areas or food. Wind is still important to me and will always be!
Deer look up a lot more so it's also very important to be well concealed and positioned to where you're aren't set up too close to the funnel or trail you're hunting. I prefer sitting in the shade,20-22 feet high and 25-33 yards from where I intend to get a shot opportunity.
I'm with Ric. For me, access is paramount. Not all properties lend themselves to great access, so in those cases I start with the best terrain features. With the varying topography of the Appalachian foothills, knowledge of the terrain and how deer use it is crucial. I take wind direction, the sun, food, water and cover in to consideration like most as well. I also try to hang in multi-trunked trees, trees that hold their leaves well in to fall, or clusters of trees to hide my big ass. I'll tack on 5-10 yards to the shot to get the perfect tree.